研究员-- 干细胞与再生医学创新研究院

研究队伍

研究员

王强

[研究员]

胚胎发育信号转导研究组

联系方式 qiangwang@ioz.ac.cn +86-10-64807895 http://www.biomembrane.ioz.cas.cn/yjz/wangqiang/pi/

教育经历

1999年山东大学生命科学院毕业，2004年在山东大学获得博士学位。

工作经历

2004-2008年在清华大学生物系从事博士后研究，2008年到中科院动物所任副研究员，2013年任研究员。

研究方向

主要从事胚胎形态发生领域的研究工作，深入探讨胚胎如何由一个形态均一的卵裂球发育为具有明显的头尾、背腹及左右等不对称特征的个体。

代表性发表论文

Yan Y, Ning G, Li L, Liu J, Yang S, Cao Y, Wang Q*. (2019). The BMP ligand Pinhead together with Admp supports the robustness of embryonic patterning. Science Advances 5, eaau6455.
Liu J, Zhu C, Ning G, Yang L, Cao Y, Huang S*, Wang Q*. (2019). Chemokine signaling links cell-cycle progression and cilia formation for left-right symmetry breaking. PLOS Biology 17, e3000203.
Li L, Ning G, Yang S, Yan Y, Cao Y, Wang Q*. (2019). BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish. PLOS Genetics 15, e1007996.
Wei S., Dai M., Liu Z., Ma Y., Shang H., Cao Y., Wang Q*. (2017). The guanine nucleotide exchange factor Net1 facilitates the specification of dorsal cell fates in zebrafish embryos by promoting maternal β-catenin activation. Cell Research 27, 202-225.
Liu Z, Ning G, Xu R, Cao Y, Meng A*, Wang Q*. (2016). Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation. Nature Communications 7, 12603.
Liu H., Li X., Ning G., Zhu S., Ma X., Liu X., Liu C., Huang M., Schmitt I., Wüllner U., Niu Y., Guo C.*, Wang Q.*, Tang TS*. (2016). The Machado-Joseph disease deubiquitinase Ataxin-3 regulates the stability and apoptotic function of p53. PLOS Biology 14, e2000733.
Ma Y, Liu X, Liu Z, Wei S, Shang H, Xue Y, Cao Y, Meng A*, Wang Q*. (2015). The chromatin remodeling protein Bptf promotes posterior neuroectodermal fate by enhancing Smad2-activated wnt8a expression. Journal of Neuroscience 35, 8493- 8506.
Ning, G., Liu, X., Dai, M., Meng, A.*, and Wang, Q*. (2013). MicroRNA-92a upholds Bmp signaling by targeting noggin3 during pharyngeal cartilage formation. Developmental Cell 24, 283-295.
Wang, Q., Huang, Z., Xue, H., Jin, C., Ju, X.L., Han, J.D., and Chen, Y.G*. (2008). MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4. Blood 111, 588-595.
Ma, J#, Wang, Q#, Fei, T., Han, J.D., and Chen, Y.G*. (2007). MCP-1 mediates TGF-β-induced angiogenesis by stimulating vascular smooth muscle cell migration. Blood 109, 987-994. (#Co-first author).